Here's what I've done so far (soo many games!)
wow! can't wait for more MegaDrive games
here's a list with Top 100 Most Wanted Sega MD/Genesis games:
[Folder name] [File name]
12-in-1 (Unl)
16 Ton (J)
3 Ninjas Kick Back
777 Casino (Unl)
AAAHH!!! Real Monsters (W)
Aah! Harimanada (J)
Action 52-in-1 (Unl) [c]
Adventures of Batman and Robin, The (E)
Akumajou Dracula - Vampire Killer (J)
Aladdin (E)
Aladdin
Alien 3 (W)
Alien Soldier (E)
Animaniacs (E)
Another World (E)
Asterix and the Power of The Gods (E) (M4)
Bare Knuckle III (J)
Batman Forever (W)
Batman Returns
Battletech
Battletoads and Double Dragon [c]
Beavis and Butt-head
Beyond Oasis
Boogerman
Bugs Bunny in Double Trouble
Captain America and the Avengers (E)
Castlevania - Bloodlines
Castlevania - The New Generation (E)
Comix Zone (E)
Command & Conquer (Beta)
Commandos (R)
Contra - Hard Corps
Contra - The Hard Corps (J)
Desert Strike - Return to the Gulf
Donald Duck in Maui Mallard (E)
Doom Troopers - The Mutant Chronicles [c]
Double Dragon 2 (J)
Double Dragon 3 - The Arcade Game
Double Dragon V - The Shadow Falls
Dragon Ball Z - Buu Yuu Retsuden (J)
Dragon Ball Z - L'Appel du Destin (F)
Duke Nukem 3D (W)
Dune - The Battle for Arrakis (E)
Dune - The Building of a Dynasty
Earthworm Jim (E)
Earthworm Jim 2
Fatal Fury 2 (UE) [c]
FIFA Soccer 2000 Gold Edition (W) [p1]
FIFA Soccer 99 (R) [p1]
Final Fantasy (R)
Garfield - Caught in the Act (UE)
Gargoyles
Golden Axe (W) (REV 00)
Golden Axe II (W)
Golden Axe III (JE)
Harry Potter (R)
Hercules (J) [p1]
James Pond 3 - Operation Starfish (W)
Jurassic Park 2 - The Lost World (W)
King of Fighters '98, The (Unl)
Lion King, The (W)
Mega Games 10 in 1 (W)
Michael Jackson's Moonwalker (W) (REV 00)
Mortal Combat 5 (Unl) [c]
Mortal Kombat (W) (REV 00)
Mortal Kombat 3 (E)
Mortal Kombat 3
Mortal Kombat II (W)
Phantasy Star - The End of the Millenium
Prince of Persia (E)
Road Rash 3 (W)
Shining Force II - Return of the King (J)
Simpsons, The - Bart's Nightmare (W)
Sonic 3D Blast (W)
Sonic and Knuckles & Sonic 1 (W)
Sonic and Knuckles & Sonic 2 (W)
Sonic and Knuckles & Sonic 3 (W)
Sonic and Knuckles (W)
Sonic Compilation (E)
Sonic Eraser (J)
Sonic The Hedgehog (MP)
Sonic The Hedgehog (W) (REV 00)
Sonic The Hedgehog 2 (W)
Sonic The Hedgehog 3 (E)
Sonic The Hedgehog 3
Spider-Man and Venom - Separation Anxiety (W)
Spider-Man and X-Men - Arcade's Revenge
Street Fighter II Special Champion Edition
Street Fighter II Turbo
Streets of Rage 2
Streets of Rage 3
Super Mario World (Unl) [c]
Super Street Fighter II - The New Challengers [c]
Teenage Mutant Ninja Turtles - Return of the Shredder (J)
Tiny Toon Adventures - Acme All-Stars (E)
Toy Story (E)
Ultimate Mortal Kombat 3
Worms (E)
WWF Wrestlemania Arcade (W) (Sep 1995)
X-Men 2 - Clone Wars (W)
Total number of folders = 0
Total number of files = 100
if you cover these most people will be satisfied
whatever you do
please add Ultimate Mortal Kombat 3 and Mortal Kombat 3 on your short list